Sinorhizobium medicae genes whose regulation involves the ActS and/or ActR signal transduction proteins.

@article{Fenner2004SinorhizobiumMG,
  title={Sinorhizobium medicae genes whose regulation involves the ActS and/or ActR signal transduction proteins.},
  author={Beau J. Fenner and Ravi P. Tiwari and Wayne Gerald Reeve and Michael J. Dilworth and Andrew R. Glenn},
  journal={FEMS microbiology letters},
  year={2004},
  volume={236 1},
  pages={
          21-31
        }
}
ActS-ActR proteins belong to a highly conserved family of two-component signal transduction systems involved in global regulation in the alpha-proteobacteria; they were first identified in Sinorhizobium medicae (previously Sinorhizobium meliloti) as essential for acid-tolerance. This paper reports on the identification of genes regulated by ActS and/or ActR in S. medicae. To do this, random gusA fusions were created in S. medicae to follow gene transcription in an actS chromosomal knockout… Expand
Two-component regulatory system ActS/ActR is required for Sinorhizobium meliloti adaptation to oxidative stress.
TLDR
The findings revealed that the ActS/ActR system is a key redox regulator in S. meliltoi and provides a new cue to understanding Rhizobium-legume symbiosis. Expand
New Target Genes Controlled by the Bradyrhizobium japonicum Two-Component Regulatory System RegSR
TLDR
The comparative analysis of wild-type and delta regR cells grown under oxic and microoxic conditions revealed that expression of almost 250 genes is dependent on RegR, a result that underscores the important contribution of RegR to oxygen- or redox-regulated gene expression in B. japonicum. Expand
Characterization of sigma factors of Sinorhizobium meliloti involved in stress response
Alternative sigma factors play an important role in that they can respond with transcriptional activation to the presence of adverse conditions in their environment. The presence of multiple sigmaExpand
Role of the Sinorhizobium meliloti global regulator Hfq in gene regulation and symbiosis.
TLDR
The RNA-binding protein Hfq is a global regulator which controls diverse cellular processes in bacteria and a deletion of hfq resulted in a reduced symbiotic efficiency, although the mutant was still able to initiate nodule development and differentiate into bacteroids. Expand
FixJ: a Major Regulator of the Oxygen Limitation Response and Late Symbiotic Functions of Sinorhizobium meliloti
TLDR
This study revealed that FixJ has no other direct targets besides those already known, and proposed an updated model of the FixJ regulon, involved in the regulation of functions such as denitrification or amino acid/polyamine metabolism and transport. Expand
Characterization and identification of environmental stress tolerance mechanisms in Sinorhizobium meliloti
TLDR
The use of bacterial genetics to characterize how metabolism and the production of polysaccharides affect the survival of strains under salt and acidic pH stress is described, consistent with the hypothesis that mechanisms used by rhizobia to tolerate diverse environmental conditions directly interact with the symbiotic process. Expand
The NtrY/NtrX System of Sinorhizobium meliloti GR4 Regulates Motility, EPS I Production, and Nitrogen Metabolism but Is Dispensable for Symbiotic Nitrogen Fixation.
TLDR
It is shown that NtrY/NtrX allows for optimal expression of denitrification and nifA genes under microoxic conditions in response to nitrogen compounds, and this study extends the knowledge of the complex role played by NTrY/ NtrX in S. meliloti. Expand
Novel Genes and Regulators That Influence Production of Cell Surface Exopolysaccharides in Sinorhizobium meliloti
TLDR
A genetic screen to isolate mutants with mucoid colonial morphologies that suggest EPS overproduction and identify a new protein-coding gene, emmD, which may be involved in the regulation of EPS-I production as part of the EmmABC three-component regulatory circuit. Expand
Genes commonly involved in acid tolerance are not overexpressed in the plant microsymbiont Mesorhizobium loti MAFF303099 upon acidic shock
TLDR
Overall, this study suggests a transcriptional response to acidic shock of M. loti distinct from other rhizobia, with a significant number of transcriptional regulators and ABC transporter genes are overexpressed. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 64 REFERENCES
Genetic regulation of nitrogen fixation in rhizobia.
  • H. Fischer
  • Biology, Medicine
  • Microbiological reviews
  • 1994
TLDR
Although the involvement of FixLJ and FixK in nifA regulation is remarkably different in the three rhizobial species discussed here, they constitute a regulatory cascade that uniformly controls the expression of genes (fixNOQP) encoding a distinct cytochrome oxidase complex probably required for bacterial respiration under low-oxygen conditions. Expand
Expression of the fixR-nifA Operon inBradyrhizobium japonicum Depends on a New Response Regulator, RegR
TLDR
The newly identified RegR protein may be regarded as a master regulator in the NifA-dependent network controlling nif and fix gene expression in B. japonicum and belongs to the family of response regulators of two-component regulatory systems. Expand
Acid tolerance in Rhizobium meliloti strain WSM419 involves a two-component sensor-regulator system.
TLDR
Data implicate a two-component sensor-regulator protein pair in acid tolerance in R. meliloti and suggest their involvement in pH sensing and/or response by these bacteria. Expand
β-Glucuronidase (GUS) transposons for ecological and genetic studies of rhizobia and other Gram-negative bacteria
TLDR
A series of transposons are described which contain the gusA gene, encoding β-glucuronidase (GUS), expressed from a variety of promoters, both regulated and constitutive, which constitute powerful new tools for studying the ecology and population biology of bacteria in the environment and in association with plants. Expand
Interacting Regulatory Circuits Involved in Orderly Control of Photosynthesis Gene Expression in Rhodobacter sphaeroides 2.4.1
TLDR
Results obtained suggested that FnrL is not involved in the transduction of the inhibitory signal, by which PS gene expression is "silenced," emanating from the cbb(3) oxidase encoded by the ccoNOQP operon under aerobic conditions, and revealed that anaerobic induction of the bchE, hemN, and hemZ genes, which areinvolved in the tetrapyrrole biosynthetic pathways, requires Fnrl. Expand
Cascade regulation of nif gene expression in Rhizobium meliloti
TLDR
It is proposed that FixL, which has features of a transmembrane protein, senses an environmental signal and transduces it to FixJ, a transcriptional activator of nif and fix genes. Expand
ActP controls copper homeostasis in Rhizobium leguminosarum bv. viciae and Sinorhizobium meliloti preventing low pH‐induced copper toxicity
TLDR
It is shown that copper homeostasis is an essential mechanism for the acid tolerance of these root nodule bacteria since it prevents this heavy metal from becoming overtly toxic in acidic conditions. Expand
From redox flow to gene regulation: role of the PrrC protein of Rhodobacter sphaeroides 2.4.1.
TLDR
It is suggested that PrrC is located upstream of the two-component PrrBA activation system in the signal transduction pathway but downstream of the cbb(3) cytochrome c oxidase and its "transponder" CcoQ. Expand
Multiple regulators and their interactions in vivo and in vitro with the cbb regulons of Rhodobacter capsulatus.
TLDR
In addition to the rather specific control exerted by CbbR, a more globally significant regulatory system, the RegA-RegB (PrrA-PrrB) two-component system, was found to contribute to transcriptional regulation of each cbb operon. Expand
Phosphorylation, dephosphorylation and DNA-binding of the Bradyrhizobium japonicum RegSR two-component regulatory proteins.
TLDR
The RegSR proteins of B. japonicum exhibit functional properties in vitro that are typical of two-component regulatory systems, including phosphorylated RegR and a truncated soluble variant of RegS (RegS(C)), both as N-terminally His(6)-tagged proteins. Expand
...
1
2
3
4
5
...