Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report.

@article{Woodworth2007SinonasalSP,
  title={Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report.},
  author={Bradford A Woodworth and Rachel A. Wood and John E. Baatz and Rodney J. Schlosser},
  journal={Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery},
  year={2007},
  volume={137 1},
  pages={34-8}
}
OBJECTIVE To measure alterations in SPA1, A2, and D gene expression in various forms of inflammatory chronic rhinosinusitis (CRS). STUDY DESIGN AND SETTING Sinus mucosal biopsies were performed in patients with allergic fungal rhinosinusitis (AFS), CRS with nasal polyposis, cystic fibrosis (CF), and controls. SP mRNA was measured with quantitative polymerase chain reaction. RESULTS Patients with CF (n = 4) showed significantly increased SPA1 (82-fold), SPA2 (100-fold), and SPD (47-fold… CONTINUE READING

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