Sinoatrial node electrical activity modulates pulmonary vein arrhythmogenesis.

  title={Sinoatrial node electrical activity modulates pulmonary vein arrhythmogenesis.},
  author={Yao-Chang Chen and Yen-Yu Lu and Chen-Chuan Cheng and Yung-Kuo Lin and Shih Ann Chen and Yi-Jen Chen},
  journal={International journal of cardiology},
  volume={173 3},
BACKGROUND Sinoatrial node (SAN) dysfunction increases the occurrences of atrial fibrillation (AF). The pulmonary veins (PVs) play a critical role in the pathophysiology of AF. The purpose of this study was to evaluate whether SAN electrical activity can modulate PV arrhythmogenesis. METHODS Conventional microelectrodes and multi-electrode array system were used to simultaneously record the electrical activity and conduction properties of rabbit SAN and PV tissue preparations with and without… CONTINUE READING
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