Sinnlose allergietests* : Stellungnahme der Fachkommission der Schweizerischen Gesellschaft für Allergologie und Immunologie (SGAI) zur IgG/IG4-Bestimmung gegen Nahrungsmittel

  title={Sinnlose allergietests* : Stellungnahme der Fachkommission der Schweizerischen Gesellschaft f{\"u}r Allergologie und Immunologie (SGAI) zur IgG/IG4-Bestimmung gegen Nahrungsmittel},
  author={B. W{\"u}thrich and P. C. Frei and A. Bircher and E. Dayer and C. Hauser and W. Pichler and P. Schmid-Grendelmeier and F. Spertini and D. Olgiati and U. M{\"u}ller},
Bereits in der Vergangenheit sah sich die Spezialistenkommission der SGAI veranlasst, zur Bedeutung und Indikation einer breiten IgG-Bestimmung gegen Nahrungsmittel in der Schweizerischen Ärztezeitung Stellung zu nehmen [1, 2]. Die Leiter der Schweizerischen Allergiepolikliniken und die praktizierenden Allergologen und klinischen Immunologen FMH werden in der letzten Zeit bei zugewiesenen Patienten vermehrt mit Resultaten von IgG-Antikörperbestimmungen gegen eine breite Palette von… Expand
2 Citations
Ungeeignete Testverfahren in der Allergologie
Critical observation and quick analysis of and clear comments to unqualified methods by the scientific medical societies are more important than ever, as inappropriate test methods are increasingly utilized to diagnose allergy. Expand


Stellenwert und Indikation der Bestimmung spezifischer IgE- und IgG-Antikörper in der Allergiediagnostik
In der klinischen Allergologie werden Patienten betreut, die an sehr unterschiedlichen Krankheiten leiden, so z.B. an Rhinitis, Asthma, Urtikaria, verschiedenen Ekzemen oder an Überempfindlichkeitsreaktionen auf Nahrungsmittel, Arzneimittel und Wespengift. Expand
Allergen‐specific IgG4 in atopic disease
The position with respect to the use of IgG4 antibodies to monitor immunotherapy is that this use of lgG4 antibody assays is justifiable, but its value should not be overrated. Expand
Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial
Food elimination based on IgG antibodies may be effective in reducing IBS symptoms and is worthy of further biomedical research. Expand
Food elimination in IBS: the case for IgG testing remains doubtful.
The numbers of patients with positive responses to eggs, cow’s milk, and cashew nuts, as judged by IgG levels, are much higher than one would expect from empirical dietary studies, and the same, in my view, would follow for several other foods. Expand
The IgE and IgG subclass antibody response to foods in babies during the first year of life and their relationship to feeding regimen and the development of food allergy.
In the population of babies studied, type I hypersensitivity to egg occurred in 5% of 1-year-old babies, the predominant IgG subclass of antibodies to CAS and OV in babies is IgG1, and in the 22% of babies, there was substantially (greater than 1000-fold) less IgG4 antibody to CASand OV than in their mothers, suggesting specific exclusion of some IgG 4 antibodies. Expand
IgG and IgA antibodies to dietary antigens in food allergy and intolerance
  • R. Barnes
  • Medicine
  • Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1995
It is clear that the inclusion (or otherwise) of appropriate control subjects, particularly age-matched healthy children, is crucial to the interpretation of much published data. Expand
Treatment of Delayed Food Allergy Based on Specific Immunoglobulin G Rast Testing
  • H. S. Dixon
  • Medicine
  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2000
This preliminary, descriptive study after extensive clinical experience demonstrates specific IgG food RASTs done in 114 consecutive patients with strong positive histories for delayed food allergy, demonstrating a 71% success rate for all symptoms achieving at least a 75% improvement level. Expand
A follow‐up study of children with food allergy. Clinical course in relation to serum IgE‐ and IgG‐antibody levels to milk, egg and fish
An early, high IgG/IgE food antibody ratio seemed to be a good prognostic sign, indicating a possible blocking capacity of IgG‐antibodies. Expand
Food allergy in irritable bowel syndrome: new facts and old fallacies
These findings should encourage studies dissecting the mechanisms responsible for IgG production against dietary antigens and their putative role in IBS to be dissected. Expand
IgG food antibodies should be studied in similarly treated groups.
Regardless of the IgG results, the treatment group excluded significantly different foods to the control group, particularly those foods which appear to exacerbate symptoms of IBS. Expand