Singlet oxygen signaling: from intimate to global.

  title={Singlet oxygen signaling: from intimate to global.},
  author={Irene E. Kochevar},
  journal={Science's STKE : signal transduction knowledge environment},
  volume={2004 221},
Reactive oxidizing species (ROS), such as hydrogen peroxide, nitric oxide, superoxide anion, and singlet oxygen, can damage cells as well as initiate responses such as new gene expression. The cell response evoked is strongly dependent on several factors. The subcellular location for formation of an ROS may be especially important for a highly reactive ROS, because it diffuses only a very short distance before reacting with a cellular molecule. How does a short-lived, locally acting ROS trigger… CONTINUE READING

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