Single-walled carbon nanotube chemoresistive label-free immunosensor for salivary stress biomarkers.

@article{Tlili2010SinglewalledCN,
  title={Single-walled carbon nanotube chemoresistive label-free immunosensor for salivary stress biomarkers.},
  author={Chaker Tlili and Lakshmi N. Cella and Nosang Myung and Vivek Shetty and Ashok Mulchandani},
  journal={The Analyst},
  year={2010},
  volume={135 10},
  pages={2637-42}
}
The present work is focused on the development, analytical characterization and evaluation of selective and sensitive SWNT-chemiresistor immunosensor for the label-free detection of salivary α-amylase (SAA). SWNTs were aligned to bridge lithographically patterned gold microelectrodes using AC dielectrophoresis followed by functionalization with anti-SAA antibodies. The nano-immunosensors exhibited excellent sensitivity over the clinically relevant range (19 to 308 U ml(-1)) with a limit of… CONTINUE READING