Single-stranded DNA binding factor AtWHY1 modulates telomere length homeostasis in Arabidopsis.

@article{Yoo2007SinglestrandedDB,
  title={Single-stranded DNA binding factor AtWHY1 modulates telomere length homeostasis in Arabidopsis.},
  author={Hyun Hee Yoo and C. Stephen Kwon and Myeong Min Lee and I. K. Chung},
  journal={The Plant journal : for cell and molecular biology},
  year={2007},
  volume={49 3},
  pages={442-51}
}
Telomere homeostasis, a process that is essential for the maintenance of chromosome integrity, is regulated by telomerase and a collection of associated proteins. By mass spectrometry we have identified a new telomeric protein encoded by the AtWHY1 (Arabidopsis thaliana Whirly 1) gene in Arabidopsis. AtWHY1 specifically binds the single-stranded plant telomeric DNA sequences, but not double-stranded telomeric DNA. To gain insights into the function of AtWHY1 in telomere biogenesis, we have… CONTINUE READING

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