Single stranded (ss)RNA-mediated antiviral response against infectious laryngotracheitis virus infection

@inproceedings{AbdulCader2019SingleS,
  title={Single stranded (ss)RNA-mediated antiviral response against infectious laryngotracheitis virus infection},
  author={Mohamed Sarjoon Abdul-Cader and Upasama De Silva Senapathi and Hanaa Ahmed-Hassan and Shayan Sharif and Mohamed Faizal Abdul-Careem},
  booktitle={BMC Microbiology},
  year={2019}
}
BackgroundSingle stranded ribonucleic acid (ssRNA) binds to toll-like receptor (TLR)7 leading to recruitment of immune cells and production of pro-inflammatory cytokines, which has been shown in mammals. In chickens, synthetic ssRNA analog, resiquimod, has been shown to elicit antiviral response against infectious bursal disease virus infection. The objective of this study was to determine the innate host responses activated by the pre-hatch in ovo administration of resiquimod against… CONTINUE READING
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