Single-step identification of all length polymorphisms in the UGT1A1 gene promoter.

Abstract

AIM To provide a sensitive genetic screening method for rapid identification of all known length polymorphisms in the promoter region of the uridine 5'-diphosphoglucose glucuronosyltransferase (UGT) 1A1 gene comprising (TA)5, (TA)7 and (TA)8 repeats as opposed to the non-mutated (TA)6 allele. METHODS The UGT1A1 promoter genotype was assessed in 115… (More)

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