Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

@article{Andrulionyt2007SingleNP,
  title={Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.},
  author={Laura Andrulionytė and Teemu Kuulasmaa and J L Chiasson and Markku Laakso},
  journal={Diabetes},
  year={2007},
  volume={56 4},
  pages={1181-6}
}
Peroxisome proliferator-activated receptor (PPAR) alpha, a transcription factor of the nuclear receptor superfamily, regulates fatty acid oxidation. We evaluated the association of single nucleotide polymorphisms (SNPs) of the PPAR-alpha gene (PPARA) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP-NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes. In the placebo group, the G… CONTINUE READING

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We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Peroxisome proliferator - activated receptor ( PPAR ) alpha , a transcription factor of the nuclear receptor superfamily , regulates fatty acid oxidation .
Peroxisome proliferator - activated receptor ( PPAR ) alpha , a transcription factor of the nuclear receptor superfamily , regulates fatty acid oxidation .
Peroxisome proliferator - activated receptor ( PPAR ) alpha , a transcription factor of the nuclear receptor superfamily , regulates fatty acid oxidation .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
Single nucleotide polymorphisms of the peroxisome proliferator - activated receptor - alpha gene ( PPARA ) influence the conversion from impaired glucose tolerance to type 2 diabetes : the STOP - NIDDM trial .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
We evaluated the association of single nucleotide polymorphisms ( SNPs ) of the PPAR - alpha gene ( PPARA ) with the conversion from impaired glucose tolerance to type 2 diabetes in 767 subjects of the STOP - NIDDM trial in order to investigate the effect of acarbose in comparison with placebo on the prevention of diabetes .
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