Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study

@article{Keyser2011SingleNP,
  title={Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study},
  author={Catherine E. de Keyser and Mark Eijgelsheim and Albert Hofman and Eric J G Sijbrands and A H Maitland-van der Zee and Cornelia M. van Duijn and Andr{\'e} G. Uitterlinden and Jacqueline C. M. Witteman and Bruno C. Stricker},
  journal={The Pharmacogenomics Journal},
  year={2011},
  volume={11},
  pages={72-80}
}
The objective of this study was to investigate whether common variation in genes involved in lipid metabolism modify the effect of statins on serum total cholesterol concentration. Statin users were identified in the Rotterdam Study, a prospective population-based cohort study of subjects >55 years of age. We studied the association between single… CONTINUE READING