Single-nucleotide polymorphisms and genome diversity in Plasmodium vivax.

@article{Feng2003SinglenucleotidePA,
  title={Single-nucleotide polymorphisms and genome diversity in Plasmodium vivax.},
  author={Xiaorong Feng and Jane M. Carlton and Deirdre A. Joy and Jianbing Mu and Tetsuya Furuya and Bernard B. Suh and Yufeng Wang and John W. Barnwell and Xin-zhuan Su},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 14},
  pages={
          8502-7
        }
}
The study of genetic variation in malaria parasites has practical significance for developing strategies to control the disease. Vaccines based on highly polymorphic antigens may be confounded by allelic restriction of the host immune response. In response to drug pressure, a highly plastic genome may generate resistant mutants more easily than a monomorphic one. Additionally, the study of the distribution of genomic polymorphisms may provide information leading to the identification of genes… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 41 CITATIONS

SNP hot-spots in the clam parasite QPX

  • BMC Genomics
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-4 OF 4 REFERENCES