Single-nucleotide polymorphisms (5p15.33, 15q25.1, 6p22.1, 6q27 and 7p15.3) and lung cancer survival in the European Prospective Investigation into Cancer and Nutrition (EPIC).

@article{Xun2011SinglenucleotideP,
  title={Single-nucleotide polymorphisms (5p15.33, 15q25.1, 6p22.1, 6q27 and 7p15.3) and lung cancer survival in the European Prospective Investigation into Cancer and Nutrition (EPIC).},
  author={Wei Wei Xun and Paul E Brennan and Anne Tjonneland and Ulla Vogel and Kim Overvad and Rudolf Kaaks and Frederico Canzian and Matthias B Schulze and Antonia Trichopoulou and Erifili Oustoglou and Zoi Giotaki and Mattias Johansson and Domenico Palli and Claudia Agnoli and Rosario Tumino and Carlotta Sacerdote and Salvatore Panico and Hendrik Bas Bueno-de-Mesquita and P. H. Peeters and Eiliv Lund and Merethe H Kumle and L. Pi{\~n}eiro Rodr{\'i}guez and Antonio Agudo and Mirella P{\'e}rez de S{\'a}nchez and L. Blanco Arriola and M D Chirlaque and Aurelio Barricarte and Göran Hallmans and Torgny Rasmuson and Kay-Tee Khaw and Nicholas J Wareham and Timothy J Key and Elio Riboli and Paolo Vineis},
  journal={Mutagenesis},
  year={2011},
  volume={26 5},
  pages={
          657-66
        }
}
The single-nucleotide polymorphisms (SNPs) rs402710 (5p15.33), rs16969968 and rs8034191 (15q25.1) have been consistently identified by genome-wide association studies (GWAS) as significant predictors of lung cancer risk, while rs4324798 (6p22.1) was previously found to influence survival time in small-cell lung cancer (SCLC) patients. Using the same population of one of the original GWAS, we investigated whether the selected SNPs and 31 others (also identified in GWAS) influence survival time… CONTINUE READING
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