Single neurons in prefrontal cortex encode abstract rules

@article{Wallis2001SingleNI,
  title={Single neurons in prefrontal cortex encode abstract rules},
  author={Jonathan D. Wallis and K. C. Anderson and Earl K. Miller},
  journal={Nature},
  year={2001},
  volume={411},
  pages={953-956}
}
The ability to abstract principles or rules from direct experience allows behaviour to extend beyond specific circumstances to general situations. For example, we learn the ‘rules’ for restaurant dining from specific experiences and can then apply them in new restaurants. The use of such rules is thought to depend on the prefrontal cortex (PFC) because its damage often results in difficulty in following rules. Here we explore its neural basis by recording from single neurons in the PFC of… CONTINUE READING
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