Single multivalent vaccination boosted by trickle larval infection confers protection against experimental lymphatic filariasis.

@article{Joseph2013SingleMV,
  title={Single multivalent vaccination boosted by trickle larval infection confers protection against experimental lymphatic filariasis.},
  author={Sharon Joseph and Kalyanasundaram Ramaswamy},
  journal={Vaccine},
  year={2013},
  volume={31 33},
  pages={3320-6}
}
The multivalent vaccine BmHAT, consisting of the Brugia malayi infective larval (L3) antigens heat shock protein12.6 (HSP12.6), abundant larval transcript-2 (ALT-2) and tetraspanin large extra cellular loop (TSP-LEL), was shown to be protective in rodent models from our laboratory. We hypothesize that since these antigens were identified using protective… CONTINUE READING