Single molecules can operate as primitive biological sensors, switches and oscillators

@inproceedings{HernansaizBallesteros2018SingleMC,
  title={Single molecules can operate as primitive biological sensors, switches and oscillators},
  author={Rosa D. Hernansaiz-Ballesteros and Luca Cardelli and Attila Csik{\'a}sz-Nagy},
  booktitle={BMC Systems Biology},
  year={2018}
}
BackgroundSwitch-like and oscillatory dynamical systems are widely observed in biology. We investigate the simplest biological switch that is composed of a single molecule that can be autocatalytically converted between two opposing activity forms. We test how this simple network can keep its switching behaviour under perturbations in the system.ResultsWe show that this molecule can work as a robust bistable system, even for alterations in the reactions that drive the switching between various… CONTINUE READING
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