Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure.

Abstract

A framed photo of DNA: A pair of photoresponsive oligonucleotides containing azobenzene moieties was introduced into double-stranded DNA within the cavity of a DNA nanostructure (see scheme). The two dsDNAs, in contact at the center, were dissociated using UV irradiation and hybridized with visible light; this was directly observed using high-speed atomic… (More)
DOI: 10.1002/anie.201205247

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@article{Endo2012SinglemoleculeVO, title={Single-molecule visualization of the hybridization and dissociation of photoresponsive oligonucleotides and their reversible switching behavior in a DNA nanostructure.}, author={Masayuki Endo and Yangyang Yang and Yuki Suzuki and Kumi Hidaka and Hiroshi Sugiyama}, journal={Angewandte Chemie}, year={2012}, volume={51 42}, pages={10518-22} }