Single-molecule visualization of a formin-capping protein ‘decision complex' at the actin filament barbed end

Abstract

Precise control of actin filament length is essential to many cellular processes. Formins processively elongate filaments, whereas capping protein (CP) binds to barbed ends and arrests polymerization. While genetic and biochemical evidence has indicated that these two proteins function antagonistically, the mechanism underlying the antagonism has remained… (More)
DOI: 10.1038/ncomms9707

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