Single-molecule spectroscopy of amino acids and peptides by recognition tunnelling.


The human proteome has millions of protein variants due to alternative RNA splicing and post-translational modifications, and variants that are related to diseases are frequently present in minute concentrations. For DNA and RNA, low concentrations can be amplified using the polymerase chain reaction, but there is no such reaction for proteins. Therefore… (More)
DOI: 10.1038/nnano.2014.54


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