Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia.

@article{Toma2014SinglemoleculeL1,
  title={Single-molecule long-read 16S sequencing to characterize the lung microbiome from mechanically ventilated patients with suspected pneumonia.},
  author={Ian Toma and Marc O. Siegel and John F Keiser and A. N. Yakovleva and Alvin Kim and Lionel Davenport and Joseph M. Devaney and Eric P. Hoffman and Rami Alsubail and Keith A. Crandall and Eduardo Castro-Nallar and Marcos P{\'e}rez-Losada and Sarah K. Hilton and Lakhmir S. Chawla and Timothy A. McCaffrey and Gary L. Simon},
  journal={Journal of clinical microbiology},
  year={2014},
  volume={52 11},
  pages={3913-21}
}
In critically ill patients, the development of pneumonia results in significant morbidity and mortality and additional health care costs. The accurate and rapid identification of the microbial pathogens in patients with pulmonary infections might lead to targeted antimicrobial therapy with potentially fewer adverse effects and lower costs. Major advances in… CONTINUE READING