Single-molecule force spectroscopy using the NanoTracker optical tweezers platform: from design to application.

@article{Wozniak2009SinglemoleculeFS,
  title={Single-molecule force spectroscopy using the NanoTracker optical tweezers platform: from design to application.},
  author={Amber Rose Wozniak and Joost van Mameren and S. P. Marchese Ragona},
  journal={Current pharmaceutical biotechnology},
  year={2009},
  volume={10 5},
  pages={
          467-73
        }
}
Since the development of detection and analysis techniques for optical tweezers setups, there has been an ever-increasing interest in optical tweezers as a quantitative method, shifting its applications from a pure manipulation tool towards the investigation of motions and forces. With the capability of manipulation and detection of forces of a few hundred picoNewtons down to a fraction of a picoNewton, optical tweezers are perfectly suitable for the investigation of single molecules… CONTINUE READING
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