Single-molecule fluorescence in situ hybridization: Quantitative imaging of single RNA molecules

@inproceedings{Kwon2013SinglemoleculeFI,
  title={Single-molecule fluorescence in situ hybridization: Quantitative imaging of single RNA molecules},
  author={Sunjong Kwon},
  booktitle={BMB reports},
  year={2013}
}
In situ detection of RNAs is becoming increasingly important for analysis of gene expression within and between intact cells in tissues. International genomics efforts are now cataloging patterns of RNA transcription that play roles in cell function, differentiation, and disease formation, and they are demonstrating the importance of coding and noncoding RNA transcripts in these processes. However, these techniques typically provide ensemble averages of transcription across many cells. In situ… CONTINUE READING

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