Single-minded, Dmef2, Pointed, and Su(H) act on identified regulatory sequences of the roughest gene in Drosophila melanogaster

@article{Apitz2005SinglemindedDP,
  title={Single-minded, Dmef2, Pointed, and Su(H) act on identified regulatory sequences of the roughest gene in Drosophila melanogaster},
  author={Holger Apitz and Martin Str{\"u}nkelnberg and Heinz Gert de Couet and Karl-Friedrich Fischbach},
  journal={Development Genes and Evolution},
  year={2005},
  volume={215},
  pages={460-469}
}
Roughest (Rst) is a cell adhesion molecule of the immunoglobulin superfamily that has multiple and diverse functions during the development of Drosophila melanogaster. The pleiotropic action of Rst is reflected by its complex and dynamic expression during the development of Drosophila. By an enhancer detection screen, we previously identified several cis-regulatory modules that mediate specific expression of the roughest gene in Drosophila developmental processes. To identify trans-regulators… CONTINUE READING

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