Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins.

@article{LpezSnchez2007SingleMG,
  title={Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins.},
  author={Noelia L{\'o}pez-S{\'a}nchez and Zaira Gonz{\'a}lez-Fern{\'a}ndez and Michio Niinobe and Kazuaki Yoshikawa and Jose Frade},
  journal={Physiological genomics},
  year={2007},
  volume={30 2},
  pages={156-71}
}
In mammals, the type II melanoma antigen (Mage) protein family is constituted by at least 10 closely related members that are expressed in different tissues, including the nervous system. These proteins are believed to regulate cell cycle withdrawal, neuronal differentiation, and apoptosis. However, the analysis of their specific function has been complicated by functional redundancy. In accordance with previous studies in teleosts and Drosophila, we present evidence that only one mage gene… CONTINUE READING

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These proteins are believed to regulate cell cycle withdrawal , neuronal differentiation , and apoptosis .
These proteins are believed to regulate cell cycle withdrawal , neuronal differentiation , and apoptosis .
FungiNo subtypeprotists
In accordance with previous studies in teleosts and Drosophila , we present evidence that only one mage gene exists in genomes from protists , fungi , plants , nematodes , insects , and nonmammalian vertebrates . We have identified the chicken mage gene and cloned the cDNA encoding the chick Mage protein ( CMage ) .
protistsNo subtypeFungi
In accordance with previous studies in teleosts and Drosophila , we present evidence that only one mage gene exists in genomes from protists , fungi , plants , nematodes , insects , and nonmammalian vertebrates . We have identified the chicken mage gene and cloned the cDNA encoding the chick Mage protein ( CMage ) .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
In mammals , the type II melanoma antigen ( Mage ) protein family is constituted by at least 10 closely related members that are expressed in different tissues , including the nervous system .
In mammals , the type II melanoma antigen ( Mage ) protein family is constituted by at least 10 closely related members that are expressed in different tissues , including the nervous system .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
Retinal Ganglion CellsAnatomic structure is physical part ofGanglia
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
Ganglion cellAnatomic structure is physical part ofGanglia
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
CMage is expressed in specific regions of the developing nervous system including the retinal ganglion cell layer , the ventral horn of the spinal cord , and the dorsal root ganglia , coinciding with the expression of the neurotrophin receptor p75 ( p75(NTR ) ) in these regions .
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