Single immunoglobulin IL-1 receptor-related protein attenuates the lipopolysaccharide-induced inflammatory response in A549 cells.

Abstract

The lipopolysaccharide (LPS)-Toll-like receptor 4 (TLR4) signaling pathway in alveolar epithelial cells plays an important role in many pathologic processes such as acute lung injury (ALI). The single immunoglobulin IL-1 receptor-related protein (SIGIRR) is an inhibitor of LPS-TLR4 signaling, but its expression and function in alveolar epithelial cells are… (More)
DOI: 10.1016/j.cbi.2009.11.022

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Cite this paper

@article{Feng2010SingleII, title={Single immunoglobulin IL-1 receptor-related protein attenuates the lipopolysaccharide-induced inflammatory response in A549 cells.}, author={Tian Feng and Ni Yunfeng and Zhao Jinbo and Zhang Zhipei and Zhang Huizhong and Liu Li and Jiang Tao and Wang Yunjie}, journal={Chemico-biological interactions}, year={2010}, volume={183 3}, pages={442-9} }