Single-dose methotrexate for treatment of ectopic pregnancy.

  title={Single-dose methotrexate for treatment of ectopic pregnancy.},
  author={Thomas G Stovall and Frank W Ling and Leigh A. Gray},
  journal={Obstetrics and gynecology},
  volume={77 5},
Methotrexate treatment of unruptured ectopic pregnancy is safe and effective and preserves reproductive potential. Previous protocols have required multiple methotrexate doses with or without citrovorum rescue. The purpose of this study was to determine whether patients with an unruptured ectopic pregnancy 3.5 cm or less in greatest dimension could be treated with single-dose intramuscular methotrexate (50 mg/m2) without citrovorum rescue. Thirty-one patients were eligible for this outpatient… CONTINUE READING
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