Single dose intravenous thioacetamide administration as a model of acute liver damage in rats.

Abstract

Thioacetamide (TAA) has been used extensively in the development of animal models of acute liver injury. Frequently, TAA is administered intraperitoneally to induce liver damage under anaesthesia. However, it is rarely administered by intravenous injection in conscious rats. The experiments in this study were designed to induce acute liver damage by single… (More)
DOI: 10.1111/j.1365-2613.2008.00576.x

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Cite this paper

@article{Chen2008SingleDI, title={Single dose intravenous thioacetamide administration as a model of acute liver damage in rats.}, author={Tse-Min Chen and Yi-Maun Subeq and Ru-Ping Lee and Tzyy-Wen Chiou and Bang-Gee Hsu}, journal={International journal of experimental pathology}, year={2008}, volume={89 4}, pages={223-31} }