Single dose i.v. tropisetron in the prevention of postoperative nausea and vomiting after gynaecological surgery.

@article{Capouet1996SingleDI,
  title={Single dose i.v. tropisetron in the prevention of postoperative nausea and vomiting after gynaecological surgery.},
  author={V. Capouet and C De Pauw and Bernard Vernet and Daniel R Ivens and V Derijcke and Linda F M Versichelen and h c Hugo Van Aken and Brigitte Ickx and Luciana Ritter and Frank Hulstaert},
  journal={British journal of anaesthesia},
  year={1996},
  volume={76 1},
  pages={
          54-60
        }
}
In a prospective, randomized, multicentre, double-blind, placebo-controlled study, we have compared the efficacy of a single i.v. dose of tropisetron 0.5 mg, 2 mg and 5 mg in the prevention of postoperative nausea and vomiting (PONV). We studied 385 ASA class I and II female patients undergoing abdominal or vaginal gynaecological surgery, including laparoscopy. Tropisetron or placebo were administered before a standardized general anaesthetic. The frequency of vomiting in the 24-h period after… CONTINUE READING
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