Single-dose etomidate does not increase mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials and observational studies.

@article{Gu2015SingledoseED,
  title={Single-dose etomidate does not increase mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials and observational studies.},
  author={Wan-Jie Gu and Fei Wang and Lu Tang and Jing-chen Liu},
  journal={Chest},
  year={2015},
  volume={147 2},
  pages={
          335-346
        }
}
BACKGROUND The effect of single-dose etomidate on mortality in patients with sepsis remains controversial. We systematically reviewed the literature to investigate whether a single dose of etomidate for rapid sequence intubation increased mortality in patients with sepsis. METHODS PubMed, Embase, and CENTRAL (Cochrane Central Register of Controlled Trials) were searched for randomized controlled trials (RCTs) and observational studies regarding the effect of single-dose etomidate on mortality… Expand
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