Single-dose, extended-release epidural morphine (DepoDur) compared to conventional epidural morphine for post-cesarean pain.

@article{Carvalho2007SingledoseEE,
  title={Single-dose, extended-release epidural morphine (DepoDur) compared to conventional epidural morphine for post-cesarean pain.},
  author={Brendan Carvalho and Laura M Roland and Larry F Chu and Vincent A Campitelli and Edward T. Riley},
  journal={Anesthesia and analgesia},
  year={2007},
  volume={105 1},
  pages={176-83}
}
BACKGROUND A single-dose of neuraxial morphine sulfate provides good post-Cesarean analgesia; however, its efficacy is limited to the first postoperative day. In a recent phase III study, extended-release epidural morphine (EREM) formulation provided more effective, prolonged analgesia after Cesarean delivery, compared to conventional epidural morphine. However, the study protocol did not allow for the use of nonsteroidal antiinflammatory drugs, used various postoperative analgesics, and… CONTINUE READING
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