Single channel recordings of calcium-activated potassium channels in the apical membrane of rabbit cortical collecting tubules.

@article{Hunter1984SingleCR,
  title={Single channel recordings of calcium-activated potassium channels in the apical membrane of rabbit cortical collecting tubules.},
  author={Malcolm Hunter and An{\'i}bal Gil Lopes and E L Boulpaep and Gerhard H. Giebisch},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 13},
  pages={4237-9}
}
Recordings of single potassium channels from the apical membrane of rabbit cortical collecting tubule have been achieved using the patch-clamp technique. The conductive properties of the channel have been studied in inside-out patches. The slope conductance of the open channel is approximately equal to 90 pS. The channel is selective to potassium over sodium, with a selectivity ratio of 9:1. Decreasing the calcium concentration of the solution bathing the cytoplasmic face of the patch results… CONTINUE READING
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