Single-channel kinetics of BK (Slo1) channels

  title={Single-channel kinetics of BK (Slo1) channels},
  author={Yanyan Geng and Karl L. Magleby},
  booktitle={Front. Physiol.},
Single-channel kinetics has proven a powerful tool to reveal information about the gating mechanisms that control the opening and closing of ion channels. This introductory review focuses on the gating of large conductance Ca(2+)- and voltage-activated K(+) (BK or Slo1) channels at the single-channel level. It starts with single-channel current records and progresses to presentation and analysis of single-channel data and the development of gating mechanisms in terms of discrete state Markov… CONTINUE READING
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