Single-channel analysis of the electrical response of bovine aortic endothelial cells to bradykinin stimulation: contribution of a Ca2(+)-dependent K+ channel.

@article{Sauv1990SinglechannelAO,
  title={Single-channel analysis of the electrical response of bovine aortic endothelial cells to bradykinin stimulation: contribution of a Ca2(+)-dependent K+ channel.},
  author={R{\'e}my Sauv{\'e} and Mohamed Chahine and Johanne Tremblay and Pavel Hamet},
  journal={Journal of hypertension. Supplement : official journal of the International Society of Hypertension},
  year={1990},
  volume={8 7},
  pages={S193-201}
}
The contribution of Ca2(+)-dependent K+ [K(Ca2+)] channels to the electrical response of cultured bovine aortic endothelial cells following bradykinin stimulation was investigated using the patch-clamp method in the cell-attached configuration. Results indicate (1) that bradykinin activates a voltage-insensitive K(Ca2+) channel of 40 pS in 150 mmol/l KCl through a second messenger mechanism; (2) that the time-course of the K(Ca2+) channel activation process corresponds to the time-dependent… CONTINUE READING

From This Paper

Topics from this paper.
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…