Corpus ID: 214802444

Single-cells protein analysis by mass-spectrometry

@article{Slavov2020SinglecellsPA,
  title={Single-cells protein analysis by mass-spectrometry},
  author={N. Slavov},
  journal={arXiv: Quantitative Methods},
  year={2020}
}
  • N. Slavov
  • Published 2020
  • Computer Science, Biology
  • arXiv: Quantitative Methods
Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made such analysis feasible for nucleic acids, but single-cell protein analysis remains limited. Mass-spectrometry is the most powerful method for protein analysis, but its application to single cells faces three major challenges: Efficiently delivering proteins… Expand

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