Single-cell sequencing-based technologies will revolutionize whole-organism science

  title={Single-cell sequencing-based technologies will revolutionize whole-organism science},
  author={Ehud Shapiro and Tamir Biezuner and S. Linnarsson},
  journal={Nature Reviews Genetics},
  • Ehud Shapiro, Tamir Biezuner, S. Linnarsson
  • Published 2013
  • Medicine, Biology
  • Nature Reviews Genetics
  • The unabated progress in next-generation sequencing technologies is fostering a wave of new genomics, epigenomics, transcriptomics and proteomics technologies. These sequencing-based technologies are increasingly being targeted to individual cells, which will allow many new and longstanding questions to be addressed. For example, single-cell genomics will help to uncover cell lineage relationships; single-cell transcriptomics will supplant the coarse notion of marker-based cell types; and… CONTINUE READING

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