Single-cell detection by cavity ring-down spectroscopy

  title={Single-cell detection by cavity ring-down spectroscopy},
  author={Peter B. Tarsa and Aislyn D. Wist and Paul Rabinowitz and Kevin K. Lehmanna},
The implementation of cavity ring-down spectroscopy in an optical fiber resonator extends the viability of this highly sensitive technique for label-free detection of biological species. By chemically treating the surface of discrete tapered sensing regions along the length of a physically extended optical fiber resonator, we show single-cell sensitivity arising from optical scattering of the evanescent field surrounding the fiber. The observed detection limits, based on a minimum detectable… CONTINUE READING
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Appl. Phys. Lett

  • Appl. Phys. Lett
  • 2004

Chem. Phys. Lett

  • B Tarsa, P Rabinowitz, K K Lehmann
  • Chem. Phys. Lett
  • 2004

Anal. Chem

  • J B Dudek, P B Tarsa, A Velasquez, M Wladyslawski, P Rabinowitz, K K Lehmann
  • Anal. Chem
  • 2003

Opt. Lett

  • M Gupta, H Jiao, A O 'keefe
  • Opt. Lett
  • 2002

Adv. Mater. (Weinheim, Ger.)

  • O Hayden, F L Dickert
  • Adv. Mater. (Weinheim, Ger.)
  • 2001

Anal. Bioanal. Chem

  • M D Marazuela, M C Moreno-Bondi
  • Anal. Bioanal. Chem
  • 2001

J. Vac. Sci. Technol. B

  • B Ilic, D Czaplewski, +4 authors C Blatt
  • J. Vac. Sci. Technol. B
  • 2001

Biosens. Bioelectron

  • S S Iqbal, M W Mayo, J G Bruno, B V Bronk, C A Batt, J P Chambers
  • Biosens. Bioelectron
  • 2000

Int. Rev. Phys. Chem

  • G Berden, R Peeters, G Meijer
  • Int. Rev. Phys. Chem
  • 2000

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