Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

@article{Yan2013SinglecellRP,
  title={Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells},
  author={Liying Yan and Ming Yang and Hongshan Guo and Lu Yang and Jun Wu and Rong Li and Ping Liu and Ying Lian and Xiaoying Zheng and Jie Yan and Jin Huang and Ming Li and Xinglong Wu and Lu Wen and Kaiqin Lao and Ruiqiang Li and Jie Qiao and Fuchou Tang},
  journal={Nature Structural \&Molecular Biology},
  year={2013},
  volume={20},
  pages={1131-1139}
}
Measuring gene expression in individual cells is crucial for understanding the gene regulatory network controlling human embryonic development. Here we apply single-cell RNA sequencing (RNA-Seq) analysis to 124 individual cells from human preimplantation embryos and human embryonic stem cells (hESCs) at different passages. The number of maternally expressed genes detected in our data set is 22,687, including 8,701 long noncoding RNAs (lncRNAs), which represents a significant increase from 9,735… 
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