Single-cell protein analysis by mass spectrometry.

@article{Slavov2020SinglecellPA,
  title={Single-cell protein analysis by mass spectrometry.},
  author={N. Slavov},
  journal={Current opinion in chemical biology},
  year={2020},
  volume={60},
  pages={
          1-9
        }
}
  • N. Slavov
  • Published 2020
  • Computer Science, Biology, Medicine
  • Current opinion in chemical biology
  • Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made such analysis feasible for nucleic acids but single-cell protein analysis remains limited. Mass spectrometry is the most powerful method for protein analysis, but its application to single cells faces three major challenges: efficiently delivering proteins… CONTINUE READING
    5 Citations

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