• DOI:10.1016/j.cbpa.2020.04.018
Corpus ID: 219966629

Single-cell protein analysis by mass spectrometry.

@article{Slavov2020SinglecellPA,
  title={Single-cell protein analysis by mass spectrometry.},
  author={N. Slavov},
  journal={Current opinion in chemical biology},
  year={2020},
  volume={60},
  pages={
          1-9
        }
}

N. Slavov

Published 2020

Computer Science, Biology, Medicine

Current opinion in chemical biology

Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made such analysis feasible for nucleic acids but single-cell protein analysis remains limited. Mass spectrometry is the most powerful method for protein analysis, but its application to single cells faces three major challenges: efficiently delivering proteins… CONTINUE READING

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