Single bacterial cell detection with nonlinear rotational frequency shifts of driven magnetic microspheres

@article{McNaughton2007SingleBC,
  title={Single bacterial cell detection with nonlinear rotational frequency shifts of driven magnetic microspheres},
  author={B. McNaughton and Rodney R. Agayan and R. Clarke and R. Smith and R. Kopelman},
  journal={Applied Physics Letters},
  year={2007},
  volume={91},
  pages={224105}
}
  • B. McNaughton, Rodney R. Agayan, +2 authors R. Kopelman
  • Published 2007
  • Physics, Materials Science
  • Applied Physics Letters
  • Shifts in the nonlinear rotational frequency of magnetic microspheres, driven by an external magnetic field, offer a dynamic approach for the detection of single bacterial cells. We demonstrate this capability by optically measuring such frequency shifts when an Escherichia coli attaches to the surface of a 2.0μm magnetic microsphere, thereby affecting the drag of the system. From this change in drag, the nonlinear rotation rate was reduced, on average, by a factor of 3.8. Sequential bacterial… CONTINUE READING

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