Single bacterial cell detection with nonlinear rotational frequency shifts of driven magnetic microspheres

@inproceedings{McNaughton2007SingleBC,
  title={Single bacterial cell detection with nonlinear rotational frequency shifts of driven magnetic microspheres},
  author={Brandon H. McNaughton and Rodney R. Agayan and R. A. Gordon Smith and Raoul Kopelman and Roy Malcom Clarke},
  year={2007}
}
Shifts in the nonlinear rotational frequency of magnetic microspheres, driven by an external magnetic field, offer a dynamic approach for the detection of single bacterial cells. We demonstrate this capability by optically measuring such frequency shifts when an Escherichia coli attaches to the surface of a 2.0μm magnetic microsphere, thereby affecting the drag of the system. From this change in drag, the nonlinear rotation rate was reduced, on average, by a factor of 3.8. Sequential bacterial… CONTINUE READING

Similar Papers

Figures and Topics from this paper.