Single and multiple metachronous osteosarcoma tumors after therapy.

  title={Single and multiple metachronous osteosarcoma tumors after therapy.},
  author={Norman Jaffe and Peggy Pearson and Alan Yasko and Patrick Lin and Cynthia Herzog and Kevin A. Raymond},
  volume={98 11},
BACKGROUND The objective of the current study was to determine the incidence, clinical and pathologic characteristics, and outcome of patients with conventional osteosarcoma who developed metachronous tumors after treatment for the primary tumor and prevention of pulmonary metastases. METHODS The medical records of 270 pediatric patients (younger than age 18 years) were reviewed. The prevention and absence of pulmonary metastases was confirmed by chest radiographs and computerized scans of… CONTINUE READING