Single and multidose pharmacokinetic study of a vaginal micronized progesterone insert (Endometrin) compared with vaginal gel in healthy reproductive-aged female subjects.

@article{Blake2010SingleAM,
  title={Single and multidose pharmacokinetic study of a vaginal micronized progesterone insert (Endometrin) compared with vaginal gel in healthy reproductive-aged female subjects.},
  author={E. J. Blake and P. M. Norris and S. F. Dorfman and J. Longstreth and V. Yankov},
  journal={Fertility and sterility},
  year={2010},
  volume={94 4},
  pages={
          1296-301
        }
}
OBJECTIVE To determine pharmacokinetic profiles of two times a day and three times a day dosage regimens of Endometrin, a micronized progesterone vaginal insert for luteal support in assisted reproductive technology, compared with a gel. DESIGN A single-center, randomized, open-label, single-day, and multiple-day (5 days) parallel design pharmacokinetic study. SETTING University clinical research unit. PATIENT(S) Three groups of six healthy subjects, ages 18 to 40 years. INTERVENTION(S… Expand
Progesterone pharmacokinetics and pharmacodynamics with 3 dosages and 2 regimens of an effervescent micronized progesterone vaginal insert.
Pharmacokinetics and safety profile of a novel progesterone aqueous formulation administered by the s.c. route
  • M. Sator, M. Radicioni, +4 authors G. Garhöfer
  • Medicine
  • Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
  • 2013
Pharmacokinetics of Vaginal Progesterone in Pregnancy.
Can we alter pregnancy outcome by adjusting progesterone treatment at mid-luteal phase: a randomized controlled trial
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References

SHOWING 1-10 OF 30 REFERENCES
...
1
2
3
...