Single agent etoposide in gestational trophoblastic tumours. Experience at Charing Cross Hospital 1978-1987.

@article{Hitchins1988SingleAE,
  title={Single agent etoposide in gestational trophoblastic tumours. Experience at Charing Cross Hospital 1978-1987.},
  author={Robert N Hitchins and Lydia Holden and Edward Stewart Newlands and Richard H. J. Begent and GordonJ. S. Rustin and Kenneth D. Bagshawe},
  journal={European journal of cancer & clinical oncology},
  year={1988},
  volume={24 6},
  pages={
          1041-6
        }
}
Two hundred and two patients with gestational trophoblastic tumours (GTT) were treated using single agent etoposide. Patients were divided into low, medium and high risk groups using a prognostic index. Initial chemotherapy commenced with etoposide in 101 patients and 94 were accessible. Partial response (PR), defined by a log fall in serum human chorionic gonadotrophin (hCG) concentration within 1 week, occurred in 63 patients (67%) and was more common among low (5/8; 63%) and medium risk (47… CONTINUE READING
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