Single-Therapy Androgen Suppression in Men with Advanced Prostate Cancer

  title={Single-Therapy Androgen Suppression in Men with Advanced Prostate Cancer},
  author={J. Seidenfeld and D. Samson and V. Hasselblad and N. Aronson and P. Albertsen and C. Bennett and T. Wilt},
  journal={Annals of Internal Medicine},
  • J. Seidenfeld, D. Samson, +4 authors T. Wilt
  • Published 2000
  • Medicine
  • Annals of Internal Medicine
  • Androgen ablation delays clinical progression and palliates symptoms of metastatic disease in men with advanced prostate cancer (1-4). The earliest method was orchiectomy, and diethylstilbestrol (DES) subsequently became the first reversible method (5-7). Newer alternatives include luteinizing hormone-releasing hormone (LHRH) agonists, such as leuprolide, goserelin, and buserelin (8-10), and nonsteroidal antiandrogens, such as flutamide, nilutamide, and bicalutamide (11-13). Cyproterone acetate… CONTINUE READING
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