Single SPECT measures of cerebral cortical perfusion reflect time-index estimation of dementia severity in Alzheimer's disease.

@article{Ashford2000SingleSM,
  title={Single SPECT measures of cerebral cortical perfusion reflect time-index estimation of dementia severity in Alzheimer's disease.},
  author={John Wesson Ashford and Wei Jen Shih and John J. Coupal and Rajesh Shetty and Annette Schneider and Carlyne Cool and Aamer Aleem and Vickie Kiefer and Marta S. Mendiondo and Frederick A. Schmitt},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2000},
  volume={41 1},
  pages={
          57-64
        }
}
UNLABELLED To determine the relationship between cerebral cortical blood flow loss and the temporal development of the dementia in Alzheimer's disease (AD), SPECT was studied in a cross section of AD patients with a broad range of impairment. METHODS Thirty patients with a diagnosis of probable AD had their mini-mental state examination scores transformed into time-index values to give an estimation of dementia severity relative to the developmental time course. SPECT images were obtained… CONTINUE READING

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