Single-Prolonged Stress: A Review of Two Decades of Progress in a Rodent Model of Post-traumatic Stress Disorder

@inproceedings{Lisieski2018SingleProlongedSA,
  title={Single-Prolonged Stress: A Review of Two Decades of Progress in a Rodent Model of Post-traumatic Stress Disorder},
  author={Michael J. Lisieski and A. Mark Fendrick Susan Lynne Oesterle Hye Myung Lee P Eagle and Alana C. Conti and Israel Liberzon and Shane Alan Perrine},
  booktitle={Front. Psychiatry},
  year={2018}
}
Post-traumatic stress disorder (PTSD) is a common, costly, and often debilitating psychiatric condition. However, the biological mechanisms underlying this disease are still largely unknown or poorly understood. Considerable evidence indicates that PTSD results from dysfunction in highly-conserved brain systems involved in stress, anxiety, fear, and reward. Pre-clinical models of traumatic stress exposure are critical in defining the neurobiological mechanisms of PTSD, which will ultimately aid… CONTINUE READING
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