Single Nucleotide Polymorphisms in JAZF1 and BCL11A gene are nominally associated with Type 2 Diabetes in African American Families from the GENNID Study

@inproceedings{Langberg2012SingleNP,
  title={Single Nucleotide Polymorphisms in JAZF1 and BCL11A gene are nominally associated with Type 2 Diabetes in African American Families from the GENNID Study},
  author={Kurt A. Langberg and Lijun Ma and Neeraj Kumar Sharma and Craig L Hanis and S. C. Elbein and Sandra J Hasstedt and Swapan K Das},
  booktitle={Journal of Human Genetics},
  year={2012}
}
Prior type 2 diabetes (T2D) genome-wide association studies (GWASs) have generated a list of well-replicated susceptibility loci in populations of European and Asian ancestry. To validate the trans-ethnic contribution of the single-nucleotide polymorphisms (SNPs) involved in these GWASs, we performed a family-based association analysis of 32 selected GWAS SNPs in a cohort of 1496 African-American (AA) subjects from the Genetics of NIDDM (GENNID) study. Functional roles of these SNPs were… CONTINUE READING
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