Single Nucleotide Polymorphism Analysis of European Archaeological M. leprae DNA

@inproceedings{Watson2009SingleNP,
  title={Single Nucleotide Polymorphism Analysis of European Archaeological M. leprae DNA},
  author={Claire L. Watson and Diana N J Lockwood},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND Leprosy was common in Europe eight to twelve centuries ago but molecular confirmation of this has been lacking. We have extracted M. leprae ancient DNA (aDNA) from medieval bones and single nucleotide polymorphism (SNP) typed the DNA, this provides insight into the pattern of leprosy transmission in Europe and may assist in the understanding of M. leprae evolution. METHODS AND FINDINGS Skeletons have been exhumed from 3 European countries (the United Kingdom, Denmark and Croatia… CONTINUE READING
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Variable nucleotide tandem repeat (VNTR) typing of two palaeopathological cases of lepromatous leprosy from Mediaeval England

  • GM Taylor, CL Watson, AS Bouwman, DNJ Lockwood, SA Mays
  • Journal of Archaeological Science
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