Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time.

Abstract

Single-molecule approaches to solving biophysical problems are powerful tools that allow static and dynamic real-time observations of specific molecular interactions of interest in the absence of ensemble-averaging effects. Here, we provide detailed protocols for building an experimental system that employs atomic force microscopy and a single-molecule DNA… (More)
DOI: 10.1016/bs.mie.2017.03.027

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Cite this paper

@article{Kong2017SingleMoleculeMF, title={Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time.}, author={Muwen Kong and Emily C Beckwitt and Luke Springall and Neil M. Kad and Bennett van Houten}, journal={Methods in enzymology}, year={2017}, volume={592}, pages={213-257} }