Single-Molecule Electrical Random Resequencing of DNA and RNA

@inproceedings{Ohshiro2012SingleMoleculeER,
  title={Single-Molecule Electrical Random Resequencing of DNA and RNA},
  author={Takahito Ohshiro and Kazuki Matsubara and Makusu Tsutsui and Masayuki Furuhashi and Masateru Taniguchi and Tomoji Kawai},
  booktitle={Scientific reports},
  year={2012}
}
Two paradigm shifts in DNA sequencing technologies-from bulk to single molecules and from optical to electrical detection-are expected to realize label-free, low-cost DNA sequencing that does not require PCR amplification. It will lead to development of high-throughput third-generation sequencing technologies for personalized medicine. Although nanopore devices have been proposed as third-generation DNA-sequencing devices, a significant milestone in these technologies has been attained by… CONTINUE READING

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Graphene as a subnanometre trans-electrode membrane

  • S Garaj
  • Nature 467,
  • 2010

Fabrication of the gating nanopore

  • M. Taniguchi, M. Tsutsui, K. Yokota, T. Kawai
  • device. Appl. Phys. Lett. 95,
  • 2009

Fabrication of the gating nanopore device

  • M. Taniguchi, M. Tsutsui, K. Yokota, T. Kawai
  • Appl . Phys . Lett .
  • 2009

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