Single Holliday Junctions Are Intermediates of Meiotic Recombination

Abstract

Crossing-over between homologous chromosomes facilitates their accurate segregation at the first division of meiosis. Current models for crossing-over invoke an intermediate in which homologs are connected by two crossed-strand structures called Holliday junctions. Such double Holliday junctions are a prominent intermediate in Saccharomyces cerevisiae… (More)
DOI: 10.1016/j.cell.2006.09.050

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